By Gilbert N Ling
Unique 1963 evaluate via Jay Jacobs, MD:
A actual thought of the dwelling country: The Association-Induction speculation. by means of GILBERT Ning LING, B.Sc., PH.D., Director of the dep. of Molecular Biology, Pennsylvania Hospital.
Cloth, Pp. 680, with illustrations. Blaisdell Publishing Co.,A department of Random condo. Inc., ny, London, 1962.
The writer has been famous in his box for 15 years. His paintings is praised by way of his friends, together with Dr. C. N. Yang, a Nobel Laureate in Physics. This e-book used to be written to coordinate actual chemistry, biochemistry and body structure, and clarify the various intricacies of dwelling tissue.
The contents are on such a complicated point that these accustomed to one point could be baflled by way of others. to assist in overcoming this trouble and to bridge the distance among clinical disciplines there's a word list of seventy one pages.
Unfortunately, the mathematical calculations in a few parts are too complex for a person who has no longer had really expert training.
The variety of matters is extensive; habit of Ions, nonelectrolytes and proteins; mobile potentials and permeabillty; excitatton, contraction and inhibition; the activities or enzymes, hormones, and medication; progress and neoplasm. The author's "association-induction" speculation is drawn upon to give an explanation for the phenomena or chemical motion in residing tissue. This speculation states that the associatlon among proteins and interacting debris is significantly assorted in vivo and In vitro, and that the first functionality of the polarizable resonating chain of a protein is to supply a automobile for the transmission of an inductive effect.
The ebook comprises many tables, graphs, diagrams and mathematical calculations to aid its theses. The bibliography and references are extensive.
Every general practitioner should still learn a few parts of this publication, to determine how a ways the fundamental scientists have are available in realizing the habit of residing tissue. it truly is of worth largely as a reference e-book to these whose paintings is on the uncomplicated technological know-how point.
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Additional info for A Physical Theory of the Living State the association-induction hypothesis
As we shall illustrate later, this process brings about an all-or-none type of response. In the physical world, similar phenomena are found in systems where there is such strong interaction between neighboring individual elements that they no longer act independently, but tend to act in unison. A few examples of INTRODUCTION XXXV this type of phenomenon, conventionally referred to as cooperative, are found in ferromagnetism, antiferromagnetism, and order-disorder transitions in alloys (Temperley, 1956).
The functions of these two hormones are quite different: oxytocin induces contraction of the pregnant uterus and stimulates milk ejection from the lactating breast; vasopressin acts primarily as an antidiuretic. 4. THE STRUCTURAL FORMULA OF BOVINE INSULIN. The amino-acid sequence of bovine insulin was worked out by Sanger and his associates (see Ryle et al. 1955; J. I. , 1956). 3 for the structure of oxytocin elucidated by Tuppy and du Vigneaud, et al. 5. STRUCTURAL DIFFERENCES BETWEEN BOVINE, PORCINE, SHEEP, HORSE, AND The sequence of amino-acid residues from the five different species are identical except for the indicated differences in the glycyl chain.
2. THE POSSIBLE ARRANGEMENTS OF THREE PARTICLES OF THREE DIFFERENT SPECIES IN ONE DISTRIBUTION PATTERN. a certain site and energy level can be distinguished from a configuration in which B occupies the same site and energy level. lA, if all three particles are of the same species. 3. ----- . ----o-~o THE POSSIBLE ARRANGEMENTS OF THREE PARTICLES OF TWO DIFFERENT SPECIES IN ONE DISTRIBUTION PATTERN. 2. 3). Let us designate the number of complexions possible when all particles are indistinguishable from each other as ntherm•h because it varies with the tempera- 12 Association ture.